IVRT and IVPT

At BioLink Lifesciences, we specialize in offering robust In Vitro Release Testing (IVRT) and In Vitro Permeation Testing (IVPT) services tailored for pharmaceutical companies, biotech firms, and research organizations. With a dedication to scientific precision, stringent quality standards, and innovative methodologies, we stand as a reliable partner for you. Let’s explore the core aspects of our expertise.

In Vitro Release Testing (IVRT)

In vitro release testing (IVRT) is an essential FDA-mandated assessment that supports post-approval manufacturing changes in compliance with SUPAC-SS requirements. At BioLink, we specialize in IVRT studies, providing comprehensive services to the pharmaceutical industry. Here’s what sets us apart:

  • Expertise in Discriminatory IVRT Methods

Our experienced team designs and executes discriminatory IVRT methods. These protocols allow us to compare generic drug formulations with brand products accurately. By profiling the performance characteristics of various prototype formulations, we help clients make informed decisions during topical drug product development.

  • Challenging APIs? No Problem

BioLink tailors testing protocols to meet the unique needs of clients working with challenging Active Pharmaceutical Ingredients (APIs). Our specialized approach ensures accurate results even for complex formulations.

In Vitro Permeation Testing (IVPT)

In Vitro Permeation Testing (IVPT), also known as skin permeation testing, plays a crucial role in understanding drug delivery through different skin layers. Here’s what we bring to the table

  • State-of-the-Art Franz Diffusion Cells

Our dedicated lab houses 120+ vertical Franz diffusion cells, allowing us to conduct rigorous IVPT studies. Whether you’re screening actives, characterizing skin distribution, or assessing drug delivery to specific skin layers, our advanced setup ensures reliable results.

  • Comparative Analysis and Optimization

BioLink assists in selecting optimal actives by evaluating their penetration properties. We quantify how each formulation delivers the drug to its target skin layer. Additionally, we compare your optimized formulation against marketed products, providing valuable insights for product development.